TRAFNIC /E/inj TAB. Tranexamic Acid+Mefenamic Acid 500mg/250mg Tablet relieves the pain due to muscle cramps during menstrual cycles (periods). It blocks the pain signals, relaxes the muscles and prevents sudden contractions (spasms) of muscles. This treats your pain and discomfort. You may also use a heating pad, take a hot water shower, avoid stress and try mild exercise for easing out the pain.